Medical oncology

What does oncology involve?

Oncology deals with the diagnosis and treatment of patients with tumor diseases. In veterinary medicine, oncology is a relatively young field that is rapidly advancing, making it possible nowadays to offer therapy for many dogs and cats with tumor diseases.

A referral to an oncologist can be beneficial for patients who are initially suspected of having a tumor disease as well as for patients where the presence of a tumor has already been confirmed.

The diagnosis of a tumor in a pet is often very stressful and raises many questions for pet owners. You can find answers to the most frequently asked questions further below.

Possible necessary examinations

Depending on the location of a tumor, the affected organs, and the existing symptoms, various examinations may be necessary.

Diagnostic Imaging

For many tumor patients, imaging is initially performed, with various examination methods available. Which examinations are appropriate for your pet will be discussed with you, depending on the tumor’s location, type, and existing symptoms. At Frontier Small Animal Specialists, both X-rays and ultrasound, as well as more complex examinations like computed tomography (CT) or magnetic resonance imaging (MRI), can be conducted.

Examination of Tumor Cells

For an accurate tumor diagnosis, it is usually necessary to take a sample of tumor cells for microscopic examination. Depending on the location and type of tumor, either individual tumor cells can be collected using a thin needle (fine needle aspiration) or a small portion of the tumor tissue can be surgically removed (biopsy). Fine needle aspiration is a non-invasive procedure often performed on tumors of the skin and subcutaneous tissue or tumors in the chest or abdominal cavity. The samples are immediately examined microscopically by our oncologists, allowing for a very rapid diagnosis. If sufficient cells cannot be obtained via fine needle aspiration or if there are medical reasons against this type of sample collection, a tumor biopsy may be performed. In this case, the tumor samples are sent to a pathologist, and the results are typically available within five business days.

Therapeutic options

Surgery

For many types of tumors, surgical removal is the first and most critical step in therapy. Complete surgical removal often leads to permanent cure for most benign tumors. Some malignant tumors have a low tendency to metastasize or only do so in very advanced stages of the disease; in these cases, complete surgical removal can also result in permanent cure. However, for malignant tumors prone to metastasis, it is crucial to ensure there are no existing metastases before proceeding with surgical removal. Tumor tissue removed during surgery is sent to pathology to confirm complete removal of the tumor.

Radiation

For some types of tumors, radiation therapy is possible and beneficial. It is used, for example, for tumors that cannot be completely removed surgically. In locations where complete surgical removal with sufficient margins of healthy tissue is technically impossible (e.g., head or limbs), local tumor control can be achieved through a combination of surgery followed by radiation therapy. Radiation therapy is also an option for reducing the size of large, inoperable tumors. In cases of painful bone tumors, radiation therapy can be used as a method of pain management. If radiation therapy is considered for your pet, we will discuss this option with you. Unfortunately, currently there is no radiation therapy available for dogs and cats in Bavaria. However, if you decide on radiation therapy, we can refer you to clinics further away where this treatment is available.

Chemotherapy

Chemotherapy in dogs and cats is different from that in humans. In human medicine, the goal is to cure cancer patients through intensive and aggressive treatment whenever possible. To achieve this, severe side effects and significant reductions in quality of life are often accepted.

However, for dogs and cats with cancer, the primary goal is to improve and maintain their quality of life for as long as possible through therapy. The dosage of chemotherapeutic agents is chosen to achieve an anti-tumor effect while minimizing the risk of serious side effects.

Whenever possible, we aim to treat your pet as an outpatient so that they can lead a relatively normal life at home during therapy. Chemotherapy can significantly extend the lives of affected dogs and cats, although a permanent cure is not possible for many types of cancer.

Frequently asked questions: Onkology

Is it always cancer?

Does the diagnosis of a tumor in my pet automatically mean it has cancer?

No. Animals can develop both benign and malignant tumors; only malignant tumors are referred to as “cancer.” Benign tumors typically grow relatively slowly, do not metastasize, but can still cause problems depending on the affected organs or body parts. Complete surgical removal of a benign tumor usually results in a permanent cure. Malignant tumors often grow rapidly, can invade neighboring organs or tissues, and can metastasize.

Could it be a tumor?

How do I notice that my pet might have a tumor?

The symptoms depend on the location, type, and size of the tumors. Tumors of the skin or subcutaneous tissue are visible or palpable from the outside. Tumors of internal organs can impair the function of the organ (e.g., the liver or kidneys) or cause internal bleeding. Tumors of the gastrointestinal tract can lead to diarrhea or vomiting. Sometimes tumors cause only non-specific symptoms such as weight loss or a reduced activity level. If your pet shows symptoms, please take it to a veterinarian for further examinations.

How do I make an appointment in the oncology department?

Your veterinarian can refer your pet to us if there is a suspicion that your pet might have a tumor, or if it is already known that your pet has a tumor. We kindly ask that your veterinarian sends us all existing findings and examination results before your appointment. This allows us to better plan your appointment and avoid duplicate examinations.

What happens during the first appointment?

What happens during a first visit to the Oncology Department at Frontier Small Animal Specialists?

First, we will ask you some questions about your pet’s symptoms. You will have the opportunity to ask questions and express your concerns. After that, a clinical examination of your pet will be conducted. Based on the findings, we will discuss with you which further examinations are appropriate.

Which examinations will be conducted?

Depending on the location of a tumor, the affected organs, and the existing symptoms, various examinations may be necessary.

What treatment options are there?

After a clear tumor diagnosis has been made, various treatment options are considered, which can be used either individually or in combination. Further information can be found further down on this page.

When does my pet need chemotherapy?

Chemotherapy can be used as a sole treatment, for example, in lymphatic system tumors (lymphomas) or in inoperable bladder tumors.

After the surgical removal of aggressive malignant tumors with a high risk of metastasis, chemotherapy may be administered to delay the onset of metastases.

In some tumors, chemotherapy can be used to shrink an inoperable tumor enough to enable subsequent surgical removal.

How does chemotherapy proceed?

For the pharmacological treatment of malignant tumors, various chemotherapy protocols are available. Whenever possible, we strive to conduct chemotherapy on an outpatient basis. The intervals between two chemotherapy sessions depend on the type of tumor and the chosen treatment protocol; some tumors require weekly treatments, while others may have 3-4 weeks between treatments.

Before starting chemotherapy, we will discuss in detail with you the exact procedure and the expected number of visits. Please plan for approximately one hour per chemotherapy session. Initially, your pet will undergo a clinical examination, visible or palpable tumors will be measured, and for tumors of internal organs, an ultrasound examination is often performed to assess the response to therapy. Subsequently, a venous catheter will be inserted into a leg vein, and a blood sample will be taken to ensure that your pet’s white blood cell count is high enough to proceed with chemotherapy. Before administering some medications, liver or kidney function may also be assessed via a blood sample. Most chemotherapy drugs are given intravenously, either as an injection into the venous catheter or as a short-term infusion over 15-20 minutes. Afterward, the venous catheter is removed, and you can take your pet home. Some chemotherapy drugs can also be administered in tablet form.

If the blood test shows that the white blood cell count is too low, chemotherapy may be postponed for 2-3 days. In this case, you will be given a new appointment for a repeat blood test; typically, the white blood cell count normalizes within 2-3 days, allowing chemotherapy to resume. In most cases, the dosage of the chemotherapy drug will then be slightly reduced to prevent further episodes of low white blood cells.

What are the side effects of chemotherapy?

The medications used in chemotherapy target cells that divide rapidly. These include tumor cells, which chemotherapy aims to kill, as well as healthy body cells with a high rate of division, such as those lining the gastrointestinal tract and the blood-forming cells of the bone marrow. Side effects of chemotherapy result from damage to these healthy cells. Hair loss does not occur in dogs and cats undergoing chemotherapy because their hair follicles are structured differently from those of humans. In cats, there may be temporary loss of whiskers on the face, while dogs with continuously growing or dense undercoat fur (such as various terrier breeds, poodles, Old English sheepdogs, and bearded collies) may experience thinning or coarser fur during chemotherapy.

How frequently do chemotherapy side effects occur?

Approximately 80% of all dogs and cats receiving chemotherapy experience no or only very mild side effects. It is possible that pets may show reduced appetite or be slightly tired the day after chemotherapy. Some patients may experience transient vomiting or diarrhea, which are mostly mild and resolve on their own within 1-2 days without treatment. To minimize the risk of gastrointestinal symptoms, your pet receives a prophylactic medication against nausea and vomiting alongside chemotherapy. Additionally, we provide you with tablets for nausea and vomiting to administer at home during the first few days after chemotherapy, in case your pet eats poorly or vomits.

In about 20% of patients, side effects occur within the first few days after chemotherapy that can affect their quality of life, such as repeated vomiting, frequent diarrhea, or refusal to eat. In these cases, the treatment protocol is adjusted to prevent the recurrence of side effects.

Severe life-threatening side effects are very rare. Patients experiencing severe vomiting and/or diarrhea may require hospitalization for intravenous therapy; many of these patients can be stabilized within 12-24 hours and discharged home.

A rare but serious side effect is bone marrow suppression caused by chemotherapy, which can lower the white blood cell count and impair the immune system. This can lead to life-threatening infections requiring intensive care hospitalization. Approximately one in 2000 animals receiving chemotherapy may develop such severe side effects leading to mortality.

Please contact us if you are concerned that your pet may be experiencing chemotherapy side effects.

What should I consider while my pet is undergoing chemotherapy?

After chemotherapy, small amounts of the medications are present in all body fluids and excretions of your pet. Chemotherapy drugs are very effective at killing tumor cells but can also have unwanted effects on healthy cells. Studies in human medicine have shown that patients successfully treated with chemotherapy can develop tumors years later that may have been caused by the chemotherapy drugs. Additionally, chemotherapy drugs are known to pose risks to the development of unborn children in the womb. Following general hygiene measures poses no risk to you; please refer to the information sheet “Safety Instructions During Chemotherapy” for details. Please reach out to us if you have any questions about this. Since unborn and young children are particularly vulnerable to the adverse effects of chemotherapy drugs, we generally advise that dogs and cats undergoing chemotherapy should not have direct contact with pregnant or breastfeeding women or young children.

If your pet exhibits one or more of the following symptoms during chemotherapy, please contact us immediately:

  • Severe vomiting (more than 4 times within 24 hours) or severe watery diarrhea
  • Noticeable overall discomfort (e.g., lethargy, weakness, severe restlessness)
  • Changes in breathing (constant panting, increased respiratory effort)

Dr. Silja Laberke

Specialist in Oncology in Cooperation
MRCVS DECVIM-CA (Oncology)
EBVS European Veterinary Specialist in Small Animal Oncology
RCVS recognised Specialist in Veterinary Oncology

 

Please do not hesitate to contact us if you have any questions or need assistanceWe are happy to help you. 

e-Mail: info@frontier.vet
phone: +49 (0) 89 904 29 56-0